I just read the "Mom-and-Pop Ecommerce" piece. Target One reminds me somewhat of Crayfish, particularly the face-to-face 'Edo' sales style. The company has some nice ideas, but the POS terminal is still the central repository of data for these stores, and it may be just a matter of time before the POS kings like TEC and NEC incorporate the same type of services into their offering (with a chance of a buyout of Target One on the way).
B2B business exchanges like EC-Oil and AlphaBrain, on the other hand, could be the Microsofts and de Beers of the next century.